Technology
Plasma Ablation
PLS
Ionized gas energy delivered at the skin surface — achieving precise, controlled ablation without laser contact and without ablating through to the dermis, giving tissue a natural biologic dressing for healing.
In the ecosystem — 0 MANA devices
01
What it is
Plasma Ablation converts atmospheric gas into plasma energy at the tip of a stylus, delivering brief, intense ionization to the skin surface in controlled microdots. The epidermis at each treated point undergoes desiccation rather than vaporization — the upper layer is coagulated and left intact as a natural micro-crust, which acts as a biologic dressing over the healing dermis beneath.
This mechanism distinguishes plasma from ablative lasers: there is no chromophore dependence, no residual heat damage to adjacent tissue columns, and the desiccated epidermal micro-crust is preserved rather than removed.
02
How it works in tissue
Beneath each treated point, the underlying dermis receives a controlled thermal stimulus. Fibroblasts respond with collagen synthesis; elastin density increases over the weeks following treatment. The superficial desiccated crust separates naturally within days as the epidermis regenerates beneath it, revealing the remodeled skin surface.
Because plasma energy is not wavelength-dependent, it acts on tissue by electrical ionization rather than selective chromophore absorption — making it applicable to a broader range of skin indications than light-based ablative systems, including mucosal tissue in intimate-wellness applications.
03
Where it earns its place
Plasma treatment sits at a distinctive position in a clinic's menu: it offers resurfacing-category outcomes with a no-injection, no-incision profile and an accessible price point for patients not ready for surgical or ablative laser procedures. Eyelid-area lifting, superficial lesion removal, scar treatment, and intimate-tissue remodeling are its four strongest clinical channels. Each is a separate consultation pathway with its own patient population.
Independent clinical literature
The science, in the journals
Clinical research on plasma skin regeneration and plasma radiofrequency ablation for aesthetic indications.
- 01Advances in plasma skin regenerationFoster KW, Moy RL, Fincher EF. J Cosmet Dermatol. 2008;7(3):169–179. doi:10.1111/j.1473-2165.2008.00389.x. PMID 18789051Histological studies confirmed continued collagen production, reduction of elastosis, and progressive skin rejuvenation beyond one year after treatment; FDA 510(k) clearance for rhytides, skin lesions, and actinic keratoses.View →
- 02Treatment of acne scars using the plasma skin regeneration systemGonzalez MJ, et al. Lasers Surg Med. 2008;40(2):124–127. doi:10.1002/lsm.20617. PMID 18306162Single high-energy treatment produced measurable acne-scar improvement at three and six months by physician and patient assessment.View →
- 03Facial aesthetic treatments with plasma radiofrequency ablationBaroni A, et al. J Cosmet Dermatol. 2021;20(8):2492–2496. PMID 33683794Plasma radiofrequency ablation showed versatile efficacy across a range of facial aesthetic indications with rapid recovery time, described as "one of the most versatile minimally invasive techniques."View →
Independent publications on this technology class. Findings relate to the studied protocols and devices, not to any specific MANA device.
Devices built on Plasma Ablation
Devices on this platform are being added.