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MANA

Technology

Thermic Radiofrequency

TRF

Precisely controlled thermal energy delivered deep into the dermis — the collagen remodeling engine behind MANA's body-contouring and skin-rejuvenation platforms.

In the ecosystem 6 MANA devices

Skin Rejuvenation · Body Contouring · Acne · Cellulite · Muscle Building

01

What it is

Thermic Radiofrequency works by delivering alternating electrical current into dermal tissue, generating resistive heat at a controlled depth without ablating the surface. The result is a thermal stimulus that collagen fibers respond to in two phases: immediate contraction — tightening that practitioners and patients feel on the day — and a slower secondary phase of neocollagenesis that continues over weeks and months as the tissue repairs and remodels.

Because RF energy is chromophore-independent, it works consistently across all Fitzpatrick skin types without the pigmentation risk associated with light-based alternatives at high settings.

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02

How it works in tissue

At therapeutic temperatures, collagen triple-helix structures denature partially — a precise, non-destructive injury that the body reads as a remodeling signal. Fibroblasts respond by synthesizing new, organized collagen; elastin density increases; and the extracellular matrix gradually reorganizes. The depth of thermal effect is tunable: monopolar configurations reach the deep reticular dermis and subdermal layer; bipolar or multi-polar modes concentrate energy in the mid-dermis for targeted surface work.

MANA's platforms pair TRF with complementary energies — PFEMT for muscle, ultrasound cavitation for adipose disruption — so the thermal remodeling layer works in concert with the mechanical and electromagnetic ones.

The MANA approach
Thermic radiofrequency — placeholder image, to be replaced with approved photography

03

Where it earns its place

RF treatments sit comfortably within a series-based revenue model: sessions require no topical anesthesia for most applications, no downtime, and patient results build progressively across a course — both keeping patients returning and making comparative photography straightforward. Body-contouring programs, skin-tightening courses, and acne-management protocols all draw on the same energy in different delivery modes.

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Independent clinical literature

The science, in the journals

Peer-reviewed research on radiofrequency for dermal remodeling and body contouring, selected for aesthetic and clinical-practice relevance.

Independent publications on this technology class. Findings relate to the studied protocols and devices, not to any specific MANA device.

Devices built on Thermic Radiofrequency

See the platform up close.

Thermic Radio Frequency · MANA Regenerative Biotech