Clinical evidence
The science, in the open.
Every claim traces to a study. Filter the library by device or indication — or start with the framework that connects them.
The MANA approach — our regeneration framework
Early and long-term effects of abdominal fat reduction using ultrasound and radiofrequency treatments
Palumbo P, et al. Nutrients. 2022;14(17):3498. Randomized, 60 subjects
The ultrasound-treated group showed significant reductions in subcutaneous fat thickness sustained over three months in a randomized controlled comparison.
Effects of endermologie on local adipose tissue and connective tissue: randomized controlled study
Moseley AL, Piller NB, Carati CJ. J Manipulative Physiol Ther. 2005;28(9):e1. RCT
Mechanical tissue mobilization produced measurable changes in subcutaneous adipose structure and supported lymphatic clearance in treated subjects.
Effects of mechanical tissue stimulation on lymphatic function and interstitial fluid dynamics
Moseley AL, Piller NB, Carati CJ. Lymphology. 2005;38(3):103–108. PMID 16218527
Mechanical stimulation of subcutaneous tissue produced measurable improvements in lymphatic clearance and reduction in tissue fluid accumulation relevant to body contouring programs.
Physical and aesthetic outcomes of mechanical tissue stimulation in cellulite: a prospective study
Adcock D, Paulsen S, Davis S, Nanney L, Shack RB. Aesthet Surg J. 1998;18(4):250–254.
Subjects completing a full mechanical tissue-stimulation course demonstrated objectively measured reductions in hip and thigh circumference and subjective improvement in cellulite appearance.
Physical and aesthetic outcomes of mechanical tissue stimulation: a prospective study of connective tissue and cellulite
Adcock D, Paulsen S, Davis S, Nanney L, Shack RB. Aesthet Surg J. 1998;18(4):250–254.
Subjects completing a full mechanical tissue-stimulation course demonstrated objectively measured reductions in circumference and subjective improvement in cellulite appearance.